I am a practicing internal medicine physician in Munich.   Over the past year I have been prescribing Bio Span to my patients for chronic liver problems and as an anti inflammatory in place of NSAIDS for persons who have gastric issues with Ibuprofen,  Motrin and strong prescription anti-inflammatory drugs.   The results are nothing short of extraordinary.  In many cases chronic inflammation is reduced by clearly clinically significant degrees and liver function is restored to near normal levels.  So far I have seen no adverse effects using Bio Span which is something I can not say with respect to the NSAIDS.  My patients are able to easily tolerate doses of 1 gm per day.  

I have become a huge proponent of both resveratrol and curcumin as a result of my experiences with patients.  

Pablo Bachmeier, Internist, Germany

Curcumin, the ultimate anti aging spice?

Curcumin, also known as the spice Turmeric: with its biologically active constituent curcumin, just may take the cake as the ultimate health spice, in addition to its already top billing as a staple of Indian and some Chinese cuisines. The curcumin contained in Bio Span+ is a concentrated form of the beneficial curcumoids equivalent to eating about ten grams of the spice in each capsule.

So why Curcumin? Curcumin is native to India and Indonesia, where it has been consumed and revered as both a medicine and dietary staple for over 5,000 years. Only comparatively recently has the West learned of the wide-ranging health properties of this tasty spice, largely thanks to the growing body of scientific research studies confirming and illustrating some of these specific health benefits.

Among some of the most interesting health benefits and their recent scientific findings:

Alzheimer's and Dementia: The 2003 study in Italy as published in the Italian Journal of Biochemistry showed that Turmeric protects against Alzheimer's disease by 'activating' a gene that codes for the production of the antioxidant protein bilirubin, which protects the brain against injury from free radicals which are thought to be a responsible for neurodegenerative diseases including Alzheimer's AND Dementia. Another study conducted at UCLA and published in the December 2004 issue of the Journal of Biological Chemistry, which has been confirmed by further research published online April 20, 2006, in the Journal of Agricultural and Food Chemistry, provides further insight as to how Turmeric provides multiple areas of protection against the mechanisms which cause Alzheimer's. This research was so profoundly exciting to researchers that human clinical trials to further investigate Tumeric's potential as a "preventive, therapeutic agent for Alzheimer's disease will soon be underway".

A Potent Anti-Inflammatory: Turmeric's anti-inflammatory effects have been shown to be comparable to the potent drugs hydrocortisone and phenylbutazone as well as over-the-counter anti-inflammatory agents such as Motrin. Wow! Bet you didn't think your lunchtime curry could do that, right? And, unlike lab-produced pharmaceutical drugs, Turmeric has been shown to produce no toxicity, nor the kinds of stomach problems that commonly occur with pharmaceutical anti-inflammatory drugs.

Rheumatoid Arthritis: Many clinical studies have shown that the antioxidant properties of Turmeric help fight the free radicals responsible for the painful joint inflammation of arthritis.  Turmeric's combination of antioxidant and anti-inflammatory effects explains why many people with joint diseases find relief when they use the spice regularly, and in a recent study of patients with rheumatoid arthritis, Turmeric was compared to phenylbutazone and produced comparable improvements in shortened duration of morning stiffness, lengthened walking time, and reduced joint swelling.

Cystic Fibrosis: Curcumin, the major constituent of turmeric that gives the spice its yellow color, can help correct the genetic defect that is responsible for cystic fibrosis, as suggested by an animal study published in the April 2004 issue of Science. Cystic fibrosis, a fatal disease that attacks the lungs with a thick mucus, causing life-threatening infections, and afflicts about 30,000 American children and young adults, who rarely survive beyond 30 years of age.

Colon and other Cancers: Turmeric's antioxidant effects help protect the colon cells from free radicals that can damage cellular DNA -- a significant benefit particularly in the colon where cell turnover is quite rapid. By improving liver function, it also helps the body to destroy mutated cancer cells so that they cannot spread through the body and cause more harm. Even more interesting, when Turmeric was combined with the vegetable Cauliflower, the protection against colon cancers was even more pronounced, leading researchers to believe the combination of cruciferous vegetables and curcumin could be an "effective therapy not only to prevent prostate cancer, but to inhibit the spread of established prostate cancers". Time to start eating cauliflower with turmeric!

Improved Liver Function: recent studies have shown that Turmeric increases the detoxification enzymes in the liver, so much so that one set of researchers commented, "Turmeric used widely as a spice would probably mitigate the effects of several dietary carcinogens". In our polluted, often carcinogenic-laden environment, diet and lifestyles these days, this is a good thing...

And more: from cardiovascular protection benefits (reduced heart attack and stroke risk) to serving as a great source of vitamin B6 to further overall anti-oxidization, detoxification and blood-brain benefits, the health benefits of Turmeric continue to be revealed and discovered by new scientific studies each year.

Bio Span+ Contains 300 mg of concentrated Curcumin in each daily dose of 2 Vcaps. With Biotivia you can be assured that you are getting the potency you are paying for.