Bio Shape Resveratrol Weight Loss Supplement Ingredients

Reduce appetite and cravings, Lose body fat, Increase energy, Improve healty and vitality

Trans-Resveratrol 98% 200mg* -- This ingredient alone would make an extraordinary supplement. Bio-enhanced natural Resveratrol modulates the benefits of the other appetite suppressants and metabolic agents contained in this complex and activates the SirT longevity genes. In animal studies Resveratrol prevented onsett of the normal deterioration of aging in obese subjects. The amount of Resveratrol contained in Bio Shape is that which Dr. Mehmet Oz and many other physicians and researchers recommend for optimal life extension. In multiple university studies Resveratrol has been shown to activate PGC-1 Alpha, a key regulator of energy metabolism. Once PGC-1 alpha is activated, it powerfully induces and coordinates gene expression that stimulates mitochondrial oxidative metabolism in brown fat, fiber-type switching in skeletal muscle, and multiple aspects of the fasted response in liver.

Resveratrol has been shown in numerous scientific studies to increase the number, density and efficiency of mitochondria, the fuel burning, energy producing factories in muscle cells.  If one looks at a slide containing muscle cells from a person who uses Resveratrol on a regular basis the increased number and health of the mitochondria compared to someone who does not consume Resveratrol are obvious.  The muscle of the Resveratrol user will be a deeper red in color and will contain many more mitochondria.

Fucoxanthin 150mg* -- In animal studies, fucoxanthin appeared to stimulate production of UCP1, a protein that increases the burning of fat. This protein is found in the visceral fat that surrounds internal organs in the abdomen – the type of fat linked to serious health conditions.

Organic Green Tea -- Green tea is a rich source of polyphenol catechins. Epigallocatechin gallate (EGCG) is the most active form of the catechins responsible for green tea's antioxidant and metabolic effects. Green tea also contains caffeine, which appears to act synergistically with EGCG to assist metabolism.

Garcinia cambogia 200mg* -- Garcinia Cambogia fills the glycogen stores in the liver and other tissues, thereby reducing appetite while increasing energy levels. Garcinia Cambogia lowers the production of triglycerides and may also increase thermogenesis, the burning of calories. Unlike chemical stimulants commonly used in weight loss products, Garcinia Cambogia does not act on the central nervous system. This means that Garcinia Cambogia will not cause insomnia, nervousness, changes in blood pressure or heart rate and its effectiveness will not diminish with time.

Gymnema sylvestre 200mg* -- Gymnea sylvestre is has been shown in animal studies to be able to lower the sugar available in the stomach for absorption, raise the insulin levels and block the dietary fat absorption.

Chromium 160ug* -- A trace mineral essential for the proper utilization of blood sugar. It helps lower triglyceride levels, and lowers body weight while increasing lean body mass

Why BioShape contains Fucoxanthin

Fucoxanthin is a major marine carotenoid found in edible seaweeds such as Undaria pinnatifida, commonly known as Wakame. Fucoxanthin also has anti-carcinogenec effects, apoptotic effects and free radical scavenging activity.  In a study involving obese mice, fucoxanthin was shown to suppress weight gain of white adipose tissue. So strong was this result that the researcher concluded, Because most body fat is stored in white adipose tissue, decreasing white adipose tissue weight by fucoxanthin might be a very effective approach for preventing and/or alleviating obesity.‖ Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, and Miyashita K: Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. International Journal of Molecular Medicine 18: 147-152, 2006.

The Japanese are well recognized to have the longest life expectancies in the world. Japanese women and men live longer and healthier than everyone else on Earth," says Naomi Moriyama, co-author of Japanese Women Don't Get Old or Fat: Secrets of My Mother's Tokyo Kitchen. One extensive international  study, the  United Nations World Population Prospects 2006 Revision, listed Japan as first among 194 countries in life expectancy. On the other hand, the United States, even with the best health care in the world, ranked only 34th. Not coincidentally, Japan also has the lowest obesity rate in the urbanized world. Not only can the Japanese expect to live longer but they also live healthier. A native of Japan can anticipate an average of 75 years of healthy living free of disabilities, reports WHO. http://www.webmd.com/diet/features/diets-of-world-japanese-diet

In Japan, breakfast is considered to be the most powerful meal of the day. A typical breakfast menu consists of rice, egg or fish, vegetables, fruit, green tea and miso soup. The salubrious effect of Miso soup has received increased attention in recent years. Traditionally added to Miso soup is the extraordinary seaweed known as Wakame. 

Wakame Seeweed, the source of Fucoxantin in BioShape

Wakame seaweed (Undaria pinnatifida) is an edible sea vegetable, thought to be one of the first types of marine vegetation appearing on the planet over one billion years ago. It is full of naturally occurring benefits such as Vitamin C, Fiber, Beta-Carotene, pantothenic acid and riboflavin two B Vitamins required for your body to produce energy. It also contains the broadest range of minerals of any food the same minerals found in the ocean and in human blood such as potassium, calcium, magnesium, iron, and iodine. Significantly, Wakame seaweed also has the highest concentrations of naturally occurring Fucoxanthin.

Fucoxanthin is an Important Caratenoid

Commercially, Wakame seaweed is becoming known for its Fucoxanthin, a pigment in the chloroplasts of the brown seaweed responsible for its distinctive color. Fucoxanthin is thought to be a non-stimulant thermogenic, which means it has no effect on the sympathetic nervous system and can be taken without concerns of cardiovascular exhaustion or blood pressure deregulation.
It is also said to initiate the breakdown of fats accumulated by the body’s storing of unburned protein.  Fucoxanthin extract has been reported to break apart the stored coupled proteins within the fat cell and effectively turn the stored fat back into protein to be used as energy. Fucoxanthin has been shown to increase the expression of UCP1 in white adipose tissue (WAT). WAT is typically stored by adult humans in the abdomen and is the type of fat responsible for excessive weight gain and obesity. Brown Adipose Tissue (BAT), the good fat‖, is important for both basal and inducible energy expenditure in the form of thermogenesis mediated by the expression of the tissue-specific mitochondrial uncoupling protein 1 (UCP1). In humans, UCP1 is usually expressed only in BAT and is a key component for metabolic thermogenesis, a process that prevents an excess of fat accumulation.  BAT is considered to affect the whole-body metabolism and may modify sensitivity to insulin and induce the body to resist weight gain. However, adult humans have very little BAT and most fat is stored in WAT. Regulation of UCP1 expression in tissues other than BAT is expected to reduce abdominal fat and certainly is of great interest in the weight control industry. Fucoxanthin has been shown to upregulate the expression of UCP1 in WAT, which may contribute to reducing fatty WAT stores and assist in the battle against obesity.

Studies conducted on Fucoxanthin-fed mice at Hokkaido University indicate that Fucoxanthin has the ability to oxidize fat and release energy by adaptive thermogenesis within WAT fat cells. Research showed a reduction of abdominal WAT weights in laboratory animals by feeding Wakame lipids. This research supports the finding that through the introduction of Fucoxanthin, UCP1 protein can be un-coupled and released from WAT.  In the Fucoxanthin-fed animals, WAT weight significantly decreased and UCP1 was expressed in the WAT, while there was no difference in WAT and little expression of UCP1 in the glycolipds-fed mice. The result indicates that Fucoxanthin up regulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight and abdominal fats. So promising was this result that the researchers succinctly concluded that diets containing fucoxanthin might prevent obesity. Accordingly, interest in fucoxanthin has increased, since its activity depends on the protein and gene expresssion. expressions of UCP1 in WAT. Maeda H., Hosokawa M., Shashima T., Takahashi N., Kawada T., Miyashita K. Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Intl J Mol Med 18: 147-152, 2006.

In a follow-up study, these same researchers determined that [T]he induction of UCP1 in WAT by food constituent would be important and could become an ideal therapy of obesity.” Maeda H., Tsukui T., Sashima T., Hosokawa M., Miyashita K. Seaweed carotenoid, fucoxanthin, as a multi-functional nutrient. Asia Pac J Clin Nutr 2008; 17 (SI): 196-199. The daily intake of fucoxanthin led to a significant reduction of total body weight. Body weights of laboratory animals fed Wakame lipid was significantly lower than that of controls, even though there were no significant differences in the mean daily dietary intake between the two groups. Essentially, the animals consumed the same amount of calories but those fed fucoxanthin did not accumulate excessive WAT. Further, Fucoxanthin intake also correlated significantly with reduced blood glucose and plasma insulin. Feeding fucoxanthin also significantly increased the level of hepatic docosahexaenoic acid (DHA), a most important n-3 functional polyunsaturated fatty acid in biological systems. The authors concluded, These multi-functionalities of fucoxanthin indicate that it is an important bioactive carotenoid that should be beneficial for the prevention of the metabolic syndrome.‖ Most pertinently the research confirmed that fucoxanthin is the active component in Wakame lipids that result in the anti-obesity effect. The implication for the weight control industry is clear.

The Fucoxanthin contained in Bio Shape is far more concentrated than that contained in what are called “pure” Fucoxanthin supplements. Wakame itself contains only 0.01% fucoxanthin. The concentrate we use in Bio Shape is 2000 times the of that in Wakame seeweed

Bio Shape is certified Vegan by the American Vegetarian Association.