Bio Quench Resveratrol Super Antioxidant is very stable at room temperature but it will not hurt to refrigerate them. Either way they will last for at least 2 years on the shelf after opening.
Resveratrol is not very water soluble therefore your body needs to produce enzymes such as bile from the liver and gall bladder to assimilate it. Therefore we recommend that you take our products along with or shortly after taking small amounts of an oily food. This stimulates the production of the necessary enzymes and facilitates absorption. Since our products are natural they can be taken on an empty stomach and will be absorbed more easily if taken at least one hour before or after consuming a substantial meal. Our products may be taken at any time however early morning is when your body best absorbs most nutrients. To prevent intracellular oxidation of the resveratrol, and this applies to many other polyphenols as well, one should take an antioxidant with one's daily resveratrol dose. Although something as simple as one gram of Vitamin C will help prevent oxidation we naturally recommend that you consider Biotivia's super fruit extract formulation, Bio Quench, as your choice of antioxidant. Bio Quench tested at an ORAC rating per gram of over 13,500. This is the highest rating for any dry compound ever tested by Brunswick Laboratories, the inventor of the ORAC test.
We have devoted quite a bit of study and research to quercetin's effect on resveratrol and resveratrol's metabolites and the issue of Sirt 1 activation. Our conclusion is that the most recent and best designed studies, including a study by one company that actually puts quercetin in their product, conclude that quercetin strongly inhibits the metabolites of resveratrol and suppresses SirT1 activation. Quercetin has been shown in numerous studies to interfere with the beneficial metabolites of resveratrol. These metabolites, particularly resveratrol glucuronide, resveratrol sulphate and picead possess important health properties. Studies also confirm that enterohepatic recirculation (recirculation by the liver) of these metabolites contributes significantly to the enhanced exposure of resveratrol in the tissues of mammals. Furthermore, quercetin's undesirable Sirt 1 suppression clearly rules it out as an ingredient in any longevity product.
If Biotivia scientists believed that quercetin would improve our products in a substantive way it would be in our interest to add it to our products. From an economic standpoint this would also benefit us, as quercetin is far less costly than the high-grade resveratrol we use in our products. A recent study by the makers of Longevinex strongly confirms our conclusion that quercetin inhibits SirT1 and possibly the other sirtuins as well. In this study a combination of resveratrol and quercetin along with the filler oat bran actually reduced SirT1 activation by a factor of 1.7 times; precisely the opposite effect one is looking for in a product designed to increase longevity.
Although resveratrol is the most publicized new longevity compound, it alone will not address your entire need for advanced nutrition; hence Bio Quench was developed. Bio Quench incorporates standardized high-quality extracts of the most potent super fruits. Each capsule contains more Goji Berry, Pomegranate, Mangosteen, Alpha Lipoic Acid, Grape Seed extract and an astonishingly high ORAC patented Apple skin extract, than is contained in most products offering only one of each of these ingredients. For example two Bio Quench capsules contain more antioxidant power than 500 quarts of the organic juice itself. In addition the daily dose provides more resveratrol than most stand alone resveratrol products, and the entire blend is bio enhanced. This not only makes Bio Quench an incredibly potent antioxidant but also an extremely economical and convenient way to obtain the best combination of super fruit extracts along with high potency, resveratrol.